Available strengths:

• Oral Granules: 25 mg, 50 mg, 75 mg

• Tablets: 75 mg, 150 mg

• Prolonged-release Tablets: 300 mg (under development)

Ivacaftor is a CFTR modulator indicated for the treatment of cystic fibrosis in patients with specific gating mutations. It enhances the function of the defective CFTR protein, improving chloride transport across cell membranes and supporting better respiratory outcomes.

This product is the generic equivalent to Kalydeco®, the reference product developed by Vertex Pharmaceuticals, which is a cornerstone in the treatment of cystic fibrosis. Kalydeco® is currently priced at approximately $300,000 per patient annually in the U.S.

Profarma’s Ivacaftor has been developed to meet stringent regulatory standards and is manufactured in an EU GMP-certified facility. 

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