The ProMer structure and length can be further adjusted according to unique features and mode of action of particular proteins.
ProMer advantages:
Manufacturing process is simple since there is no need of additional chemical modifications
Proteins constructed with ProMer technology can be effectively produced in bacteria, yeast and mammalian cells.
References:
*Construction, Purification, and Characterization of a Homodimeric Granulocyte Colony-Stimulating Factor. Molecular Biotechnology, October 2017, Volume 59, Issue 9–10, pp 374–384
**Generation of dimeric single-chain antibodies neutralizing the cytolytic activity of vaginolysin. Electronic Journal of Biotechnology, Volume 28, July 2017, Pages 52-57